10 research outputs found

    A Novel Fingerprinting Technique for Data Storing and Sharing through Clouds

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    With the emerging growth of digital data in information systems, technology faces the challenge of knowledge prevention, ownership rights protection, security, and privacy measurement of valuable and sensitive data. On-demand availability of various data as services in a shared and automated environment has become a reality with the advent of cloud computing. The digital fingerprinting technique has been adopted as an effective solution to protect the copyright and privacy of digital properties from illegal distribution and identification of malicious traitors over the cloud. Furthermore, it is used to trace the unauthorized distribution and the user of multimedia content distributed through the cloud. In this paper, we propose a novel fingerprinting technique for the cloud environment to protect numeric attributes in relational databases for digital privacy management. The proposed solution with the novel fingerprinting scheme is robust and efficient. It can address challenges such as embedding secure data over the cloud, essential to secure relational databases. The proposed technique provides a decoding accuracy of 100%, 90%, and 40% for 10% to 30%, 40%, and 50% of deleted record

    A Novel Fingerprinting Technique for Data Storing and Sharing through Clouds

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    With the emerging growth of digital data in information systems, technology faces the challenge of knowledge prevention, ownership rights protection, security, and privacy measurement of valuable and sensitive data. On-demand availability of various data as services in a shared and automated environment has become a reality with the advent of cloud computing. The digital fingerprinting technique has been adopted as an effective solution to protect the copyright and privacy of digital properties from illegal distribution and identification of malicious traitors over the cloud. Furthermore, it is used to trace the unauthorized distribution and the user of multimedia content distributed through the cloud. In this paper, we propose a novel fingerprinting technique for the cloud environment to protect numeric attributes in relational databases for digital privacy management. The proposed solution with the novel fingerprinting scheme is robust and efficient. It can address challenges such as embedding secure data over the cloud, essential to secure relational databases. The proposed technique provides a decoding accuracy of 100%, 90%, and 40% for 10% to 30%, 40%, and 50% of deleted records

    Boundedness of Riesz Potential Operator on Grand Herz-Morrey Spaces

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    In this paper, we introduce grand Herzā€“Morrey spaces with variable exponent and prove the boundedness of Riesz potential operators in these spaces

    Boundedness of Riesz Potential Operator on Grand Herz-Morrey Spaces

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    In this paper, we introduce grand Herz–Morrey spaces with variable exponent and prove the boundedness of Riesz potential operators in these spaces

    Metabolic Engineered Biocatalyst: A Solution for PLA Based Problems

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    Polylactic acid (PLA) is a biodegradable thermoplastic polyester. In 2010, PLA became the second highest consumed bioplastic in the world due to its wide application. Conventionally, PLA is produced by direct condensation of lactic acid monomer and ring opening polymerization of lactide, resulting in lower molecular weight and lesser strength of polymer. Furthermore, conventional methods of PLA production require a catalyst which makes it inappropriate for biomedical applications. Newer method utilizes metabolic engineering of microorganism for direct production of PLA through fermentation which produces good quality and high molecular weight and yield as compared to conventional methods. PLA is used as decomposing packaging material, sheet casting, medical implants in the form of screw, plate, and rod pin, etc. The main focus of the review is to highlight the synthesis of PLA by various polymerization methods that mainly include metabolic engineering fermentation as well as salient biomedical applications of PLA

    Therapeutic and Biomedical Potentialities of Terpenoids ā€“ A Review

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    Terpenoids are the most diverse and largest class of chemicals of the innumerable plant-based compounds. Plants carry out a number of essential growth and production functions using terpenoid metabolites. In contrast, most terpenoids are used in the abiotic and biotic systems for complex chemical interactions and defense. Terpenoids derived from plants mostly used humans for pharmaceutical, food, and chemical industries in the past. However, recently biofuel products have been developed by terpenoids. The metabolism of high-quality terpenoids in plants and microbes is facilitated in synthetic biology by genomic resources and emerging tools. Further focus has been given to the ecological value of terpenoids for establishing effective pesticide control approaches and abiotic stress protection. The awareness of the diverse metabolic and molecular regulatory networks for terpenoid biosynthesis needs to be increased continuously in all these efforts. This review gives an overview and highlights current improvements in our understanding of the organization, regulation, and diversiļ¬cation of core and specialized terpenoid metabolic pathways and discusses the prominent therapeutic roles of terpenoids. This review provides an overview and highlights recent literature in our understanding about the biomedical and therapeutic importance of terpenoids, regulation as well as the diversion of core and specialized metabolized terpenoid pathways

    Tandem Ullmann-Goldberg Cross-Coupling/Cyclopalladation-Reductive Elimination Reactions and Related Sequences Leading to Polyfunctionalized Benzofurans, Indoles, and Phthalanes

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    On exposure to a combination of Cu[I]- and Pd[0]-based catalysts, compounds such as 1 and 7 engage in tandem Ullmann-Goldberg cross-coupling and cyclopalladation-reductive elimination reactions to give benzofurans such as 8. Related reactions involving hetero-Michael additions of o-halogenated phenols or anilines to propiolates and the Pd[0]-catalyzed cyclization of the resulting conjugates provide, in a one-pot process, alternately functionalized benzofurans, indoles, or phthalanes.We thank the Australian Research Council and the Institute of Advanced Studies for financial support including the provision of scholarships to F.K. and M.A. as well as a postdoctoral fellowship to Y.V. F.M. thanks the Higher Education Council of the Government of Pakistan for support, and M.S. acknowledges the support of the Islamic Government of Ira

    N-Acetyl Cysteine, Selenium, and Ascorbic Acid Rescue Diabetic Cardiac Hypertrophy via Mitochondrial-Associated Redox Regulators

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    Metabolic disorders often lead to cardiac complications. Metabolic deregulations during diabetic conditions are linked to mitochondrial dysfunctions, which are the key contributing factors in cardiac hypertrophy. However, the underlying mechanisms involved in diabetes-induced cardiac hypertrophy are poorly understood. In the current study, we initially established a diabetic rat model by alloxan-administration, which was validated by peripheral glucose measurement. Diabetic rats displayed myocardial stiffness and fibrosis, changes in heart weight/body weight, heart weight/tibia length ratios, and enhanced size of myocytes, which altogether demonstrated the establishment of diabetic cardiac hypertrophy (DCH). Furthermore, we examined the expression of genes associated with mitochondrial signaling impairment. Our data show that the expression of PGC-1α, cytochrome c, MFN-2, and Drp-1 was deregulated. Mitochondrial-signaling impairment was further validated by redox-system dysregulation, which showed a significant increase in ROS and thiobarbituric acid reactive substances, both in serum and heart tissue, whereas the superoxide dismutase, catalase, and glutathione levels were decreased. Additionally, the expression levels of pro-apoptotic gene PUMA and stress marker GATA-4 genes were elevated, whereas ARC, PPARα, and Bcl-2 expression levels were decreased in the heart tissues of diabetic rats. Importantly, these alloxan-induced impairments were rescued by N-acetyl cysteine, ascorbic acid, and selenium treatment. This was demonstrated by the amelioration of myocardial stiffness, fibrosis, mitochondrial gene expression, lipid profile, restoration of myocyte size, reduced oxidative stress, and the activation of enzymes associated with antioxidant activities. Altogether, these data indicate that the improvement of mitochondrial dysfunction by protective agents such as N-acetyl cysteine, selenium, and ascorbic acid could rescue diabetes-associated cardiac complications, including DCH
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